null

SMILES: COc1ccc(cc1)C1=Nn2c(SC1C)nnc2C(C)C

InChI Key: InChIKey=DHYWZZQQXJGEOB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM438760 (US10618914, Compound UPCDC10332 | US11111253, Comp...) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1C)nnc2C(C)C |t:9| Show InChI InChI=1S/C15H18N4OS/c1-9(2)14-16-17-15-19(14)18-13(10(3)21-15)11-5-7-12(20-4)8-6-11/h5-10H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8XCR
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM438760 (US10618914, Compound UPCDC10332 | US11111253, Comp...) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1C)nnc2C(C)C |t:9| Show InChI InChI=1S/C15H18N4OS/c1-9(2)14-16-17-15-19(14)18-13(10(3)21-15)11-5-7-12(20-4)8-6-11/h5-10H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh—Of the Commonwealth System of Higher Education US Patent					Assay Description Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...				US Patent US10618914 (2020) BindingDB Entry DOI: 10.7270/Q2J38WMG
					More data for this Ligand-Target Pair