null
SMILES: COC1(C2CCCC1CN(C2)[C@@H]1C[C@H](F)C1)c1ccnc(c1)C(N)=O
InChI Key: InChIKey=HHIADIAOZVKSBG-FLFHYWOWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM438838 (US10604489, Compound 2 | US11180455, Compound 2) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM438838 (US10604489, Compound 2 | US11180455, Compound 2) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alkermes, Inc. US Patent | Assay Description Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d... | US Patent US10604489 (2020) | |||||||||||
More data for this Ligand-Target Pair |