null

SMILES: Cc1c(-c2cccc(N)c2C)c2cc(C#N)c(C)cc2n1CCCO

InChI Key: InChIKey=VANWIPMZSKAOOX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM439036 (3-(3-amino-2-methylphenyl)-1-(3-hydroxypropyl)-2,6...) Show SMILES Cc1c(-c2cccc(N)c2C)c2cc(C#N)c(C)cc2n1CCCO |(3.86,.41,;2.32,.41,;1.42,1.66,;1.89,3.12,;.86,4.27,;1.34,5.73,;2.85,6.05,;3.88,4.91,;5.38,5.23,;3.4,3.44,;4.43,2.3,;-.05,1.18,;-1.38,1.95,;-2.71,1.18,;-4.05,1.95,;-5.38,2.72,;-2.71,-.36,;-4.05,-1.13,;-1.38,-1.13,;-.05,-.36,;1.42,-.83,;1.89,-2.3,;.86,-3.44,;1.34,-4.91,;.31,-6.05,)| Show InChI InChI=1S/C21H23N3O/c1-13-10-20-18(11-16(13)12-22)21(15(3)24(20)8-5-9-25)17-6-4-7-19(23)14(17)2/h4,6-7,10-11,25H,5,8-9,23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...				US Patent US10604502 (2020)
					More data for this Ligand-Target Pair