BindingDB logo
myBDB logout

null

SMILES: Cc1cc2n(cc(-c3cncc(N)c3Cl)c2cc1C#N)-c1ccc(nc1)S(C)(=O)=O

InChI Key: InChIKey=ANGNRTJQSGIDML-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439090   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM439090
PNG
(US10604502, Ex # 78)
Show SMILES Cc1cc2n(cc(-c3cncc(N)c3Cl)c2cc1C#N)-c1ccc(nc1)S(C)(=O)=O
Show InChI InChI=1S/C21H16ClN5O2S/c1-12-5-19-15(6-13(12)7-23)17(16-9-25-10-18(24)21(16)22)11-27(19)14-3-4-20(26-8-14)30(2,28)29/h3-6,8-11H,24H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...

US Patent US10604502 (2020)


BindingDB Entry DOI: 10.7270/Q2MW2M62
More data for this
Ligand-Target Pair