null
SMILES: Cc1cc2n(cc(-c3cncc4NC(C)(C)CCc34)c2cc1C#N)[C@H]1CC[C@H](O)CC1
InChI Key: InChIKey=ODCOLSCPNXPFHT-WGSAOQKQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM439101 (3-(2,2-dimethyl-1,2,3,4-tetrahydro-1,7-naphthyridi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The... | US Patent US10604502 (2020) BindingDB Entry DOI: 10.7270/Q2MW2M62 | |||||||||||
More data for this Ligand-Target Pair |