null

SMILES: Cc1cc2n(cc(-c3cccc4NC(C)(C)CCc34)c2cc1C#N)[C@H]1CC[C@H](O)CC1

InChI Key: InChIKey=OPAJZTORWMELQN-MXVIHJGJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM439109 (3-(2,2-dimethyl-1,2,3,4-tetrahydroquinolin-5-yl)-1...) Show SMILES Cc1cc2n(cc(-c3cccc4NC(C)(C)CCc34)c2cc1C#N)[C@H]1CC[C@H](O)CC1 |r,wU:24.27,wD:27.31,(-6.2,.68,;-4.74,1.16,;-3.59,.13,;-2.13,.61,;-.8,-.16,;.35,.87,;-.28,2.27,;.49,3.61,;-.28,4.94,;.49,6.27,;2.03,6.27,;2.8,4.94,;4.34,4.94,;5.11,3.61,;6.65,3.61,;5.88,4.94,;4.34,2.27,;2.8,2.27,;2.03,3.61,;-1.81,2.11,;-2.95,3.14,;-4.42,2.67,;-5.56,3.7,;-6.65,4.79,;-.64,-1.7,;.79,-2.28,;.99,-3.81,;-.23,-4.75,;-.02,-6.27,;-1.65,-4.16,;-1.86,-2.64,)| Show InChI InChI=1S/C27H31N3O/c1-17-13-26-23(14-18(17)15-28)24(16-30(26)19-7-9-20(31)10-8-19)21-5-4-6-25-22(21)11-12-27(2,3)29-25/h4-6,13-14,16,19-20,29,31H,7-12H2,1-3H3/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...				US Patent US10604502 (2020) BindingDB Entry DOI: 10.7270/Q2MW2M62
					More data for this Ligand-Target Pair