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SMILES: F[C@@]1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1cccc(Cl)c1

InChI Key: InChIKey=UQSUFHPLRUHPAO-LJQANCHMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441759   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))		BDBM441759
PNG
((R)-3-(5-(3-Chlorophenyl)-2,3-dihydro-1H-pyrrolo[2...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClFN4O/c20-16-3-1-2-13(9-16)15-8-14-4-6-25(17(14)23-10-15)18(26)19(21)5-7-24(11-19)12-22/h1-3,8-10H,4-7,11H2/t19-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...

US Patent US10640498 (2020)


BindingDB Entry DOI: 10.7270/Q2J10663
More data for this
Ligand-Target Pair