BDBM441777 US10640533, Identification number CX13-109::US10640533, Table 1.24

SMILES: CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1

InChI Key: InChIKey=SDKAVNLYMZVQEF-ZPBGSLHZSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 441777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsin-like protease CTRL-1 (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair
Transmembrane protease serine 11D (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair
Chymotrypsin-like protease CTRL-1 (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair
Transmembrane protease serine 11D (Homo sapiens (Human))	BDBM441777 (US10640533, Identification number CX13-109 | US106...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccncc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H45N5O6/c1-23(2)19-28(32(42)36-27(30(40)33(3)22-44-33)20-25-11-13-34-14-12-25)37-31(41)26(10-9-24-7-5-4-6-8-24)35-29(39)21-38-15-17-43-18-16-38/h4-8,11-14,23,26-28H,9-10,15-22H2,1-3H3,(H,35,39)(H,36,42)(H,37,41)/t26-,27-,28-,33+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CENTRAX INTERNATIONAL, INC. US Patent					Assay Description Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...				US Patent US10640533 (2020)
					More data for this Ligand-Target Pair