null

SMILES: CC(C)Nc1cc(F)cc(c1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(C)CC3)cc2c1

InChI Key: InChIKey=WOJMCKPCXIYUON-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442795 (US10653688, Compound 2) Show SMILES CC(C)Nc1cc(F)cc(c1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(C)CC3)cc2c1 Show InChI InChI=1S/C29H31FN6O/c1-19(2)33-26-14-24(13-25(30)17-26)20-4-5-22-18-32-27(15-23(22)12-20)34-29(37)21-6-7-31-28(16-21)36-10-8-35(3)9-11-36/h4-7,12-19,33H,8-11H2,1-3H3,(H,32,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	354	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442795 (US10653688, Compound 2) Show SMILES CC(C)Nc1cc(F)cc(c1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(C)CC3)cc2c1 Show InChI InChI=1S/C29H31FN6O/c1-19(2)33-26-14-24(13-25(30)17-26)20-4-5-22-18-32-27(15-23(22)12-20)34-29(37)21-6-7-31-28(16-21)36-10-8-35(3)9-11-36/h4-7,12-19,33H,8-11H2,1-3H3,(H,32,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair