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SMILES: O=C(CN1CCCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1

InChI Key: InChIKey=UCULEGMKOWXIHT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 442813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442813 (US10653688, Compound 60 | US10653688, Compound 7) Show SMILES O=C(CN1CCCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O/c25-20(14-24-8-1-2-9-24)23-19-11-18-10-15(5-6-17(18)13-22-19)16-4-3-7-21-12-16/h3-7,10-13H,1-2,8-9,14H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442813 (US10653688, Compound 60 | US10653688, Compound 7) Show SMILES O=C(CN1CCCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O/c25-20(14-24-8-1-2-9-24)23-19-11-18-10-15(5-6-17(18)13-22-19)16-4-3-7-21-12-16/h3-7,10-13H,1-2,8-9,14H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442813 (US10653688, Compound 60 | US10653688, Compound 7) Show SMILES O=C(CN1CCCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O/c25-20(14-24-8-1-2-9-24)23-19-11-18-10-15(5-6-17(18)13-22-19)16-4-3-7-21-12-16/h3-7,10-13H,1-2,8-9,14H2,(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	404	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442813 (US10653688, Compound 60 | US10653688, Compound 7) Show SMILES O=C(CN1CCCC1)Nc1cc2cc(ccc2cn1)-c1cccnc1 Show InChI InChI=1S/C20H20N4O/c25-20(14-24-8-1-2-9-24)23-19-11-18-10-15(5-6-17(18)13-22-19)16-4-3-7-21-12-16/h3-7,10-13H,1-2,8-9,14H2,(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	247	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair