null

SMILES: CNC(=O)c1cncc(c1)-c1ccc2cnc(NC(=O)C3CCN(C)CC3)cc2c1

InChI Key: InChIKey=DSYMCAZIELVYGH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442876 (US10653688, Compound 58) Show SMILES CNC(=O)c1cncc(c1)-c1ccc2cnc(NC(=O)C3CCN(C)CC3)cc2c1 Show InChI InChI=1S/C23H25N5O2/c1-24-22(29)20-10-19(12-25-13-20)16-3-4-17-14-26-21(11-18(17)9-16)27-23(30)15-5-7-28(2)8-6-15/h3-4,9-15H,5-8H2,1-2H3,(H,24,29)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442876 (US10653688, Compound 58) Show SMILES CNC(=O)c1cncc(c1)-c1ccc2cnc(NC(=O)C3CCN(C)CC3)cc2c1 Show InChI InChI=1S/C23H25N5O2/c1-24-22(29)20-10-19(12-25-13-20)16-3-4-17-14-26-21(11-18(17)9-16)27-23(30)15-5-7-28(2)8-6-15/h3-4,9-15H,5-8H2,1-2H3,(H,24,29)(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair