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SMILES: Fc1cccc(c1)-c1cnc2N[C@]3(CCN(C3)C#N)C(=O)Nc2c1

InChI Key: InChIKey=OTEYMIAIGRFCQL-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443300 ((S)-7-(3- Fluorophenyl)- 2-oxo- 1,4-dihydro- 2H-sp...) Show SMILES Fc1cccc(c1)-c1cnc2N[C@]3(CCN(C3)C#N)C(=O)Nc2c1 |r| Show InChI InChI=1S/C17H14FN5O/c18-13-3-1-2-11(6-13)12-7-14-15(20-8-12)22-17(16(24)21-14)4-5-23(9-17)10-19/h1-3,6-8H,4-5,9H2,(H,20,22)(H,21,24)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443300 ((S)-7-(3- Fluorophenyl)- 2-oxo- 1,4-dihydro- 2H-sp...) Show SMILES Fc1cccc(c1)-c1cnc2N[C@]3(CCN(C3)C#N)C(=O)Nc2c1 |r| Show InChI InChI=1S/C17H14FN5O/c18-13-3-1-2-11(6-13)12-7-14-15(20-8-12)22-17(16(24)21-14)4-5-23(9-17)10-19/h1-3,6-8H,4-5,9H2,(H,20,22)(H,21,24)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair