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SMILES: O=C1Nc2cccnc2NCC11CCN(C1)C#N

InChI Key: InChIKey=FYLPWNSSPLONCB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443313 (2-Oxo-1,2,4,5-tetrahydrospiro[pyrido[2,3-b][1,4]di...) Show SMILES O=C1Nc2cccnc2NCC11CCN(C1)C#N Show InChI InChI=1S/C12H13N5O/c13-8-17-5-3-12(7-17)6-15-10-9(16-11(12)18)2-1-4-14-10/h1-2,4H,3,5-7H2,(H,14,15)(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443313 (2-Oxo-1,2,4,5-tetrahydrospiro[pyrido[2,3-b][1,4]di...) Show SMILES O=C1Nc2cccnc2NCC11CCN(C1)C#N Show InChI InChI=1S/C12H13N5O/c13-8-17-5-3-12(7-17)6-15-10-9(16-11(12)18)2-1-4-14-10/h1-2,4H,3,5-7H2,(H,14,15)(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair