null

SMILES: Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key: InChIKey=GUMBIBQYIWPWMC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443334 (6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...) Show SMILES Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H19N5O/c1-25-19-5-3-15(9-17(19)11-23-25)14-2-4-18-16(8-14)10-21(20(27)24-18)6-7-26(12-21)13-22/h2-5,8-9,11H,6-7,10,12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443334 (6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...) Show SMILES Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H19N5O/c1-25-19-5-3-15(9-17(19)11-23-25)14-2-4-18-16(8-14)10-21(20(27)24-18)6-7-26(12-21)13-22/h2-5,8-9,11H,6-7,10,12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443334 (6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...) Show SMILES Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H19N5O/c1-25-19-5-3-15(9-17(19)11-23-25)14-2-4-18-16(8-14)10-21(20(27)24-18)6-7-26(12-21)13-22/h2-5,8-9,11H,6-7,10,12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair