null

SMILES: O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(NS(=O)(=O)C2CC2)c1

InChI Key: InChIKey=GDJPSGZZBBIQRW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443336 (N-(3-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(NS(=O)(=O)C2CC2)c1 Show InChI InChI=1S/C22H22N4O3S/c23-14-26-9-8-22(13-26)12-17-10-16(4-7-20(17)24-21(22)27)15-2-1-3-18(11-15)25-30(28,29)19-5-6-19/h1-4,7,10-11,19,25H,5-6,8-9,12-13H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443336 (N-(3-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(NS(=O)(=O)C2CC2)c1 Show InChI InChI=1S/C22H22N4O3S/c23-14-26-9-8-22(13-26)12-17-10-16(4-7-20(17)24-21(22)27)15-2-1-3-18(11-15)25-30(28,29)19-5-6-19/h1-4,7,10-11,19,25H,5-6,8-9,12-13H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443336 (N-(3-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(NS(=O)(=O)C2CC2)c1 Show InChI InChI=1S/C22H22N4O3S/c23-14-26-9-8-22(13-26)12-17-10-16(4-7-20(17)24-21(22)27)15-2-1-3-18(11-15)25-30(28,29)19-5-6-19/h1-4,7,10-11,19,25H,5-6,8-9,12-13H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair