null

SMILES: CC(=O)Nc1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key: InChIKey=KDQRKEGIZAUQLZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443340 (N-(4-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H20N4O2/c1-14(26)23-18-5-2-15(3-6-18)16-4-7-19-17(10-16)11-21(20(27)24-19)8-9-25(12-21)13-22/h2-7,10H,8-9,11-12H2,1H3,(H,23,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443340 (N-(4-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H20N4O2/c1-14(26)23-18-5-2-15(3-6-18)16-4-7-19-17(10-16)11-21(20(27)24-19)8-9-25(12-21)13-22/h2-7,10H,8-9,11-12H2,1H3,(H,23,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443340 (N-(4-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H20N4O2/c1-14(26)23-18-5-2-15(3-6-18)16-4-7-19-17(10-16)11-21(20(27)24-19)8-9-25(12-21)13-22/h2-7,10H,8-9,11-12H2,1H3,(H,23,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair