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SMILES: Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key: InChIKey=INHRDLUVKVXEFT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443350 (6'-(2-Methylbenzo[d]thiazol-5-yl)-2'- oxo-1',4'-di...) Show SMILES Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H18N4OS/c1-13-23-18-9-15(3-5-19(18)27-13)14-2-4-17-16(8-14)10-21(20(26)24-17)6-7-25(11-21)12-22/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443350 (6'-(2-Methylbenzo[d]thiazol-5-yl)-2'- oxo-1',4'-di...) Show SMILES Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H18N4OS/c1-13-23-18-9-15(3-5-19(18)27-13)14-2-4-17-16(8-14)10-21(20(26)24-17)6-7-25(11-21)12-22/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443350 (6'-(2-Methylbenzo[d]thiazol-5-yl)-2'- oxo-1',4'-di...) Show SMILES Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H18N4OS/c1-13-23-18-9-15(3-5-19(18)27-13)14-2-4-17-16(8-14)10-21(20(26)24-17)6-7-25(11-21)12-22/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair