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SMILES: COc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1

InChI Key: InChIKey=JEMWAIVHDRSDFF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Monoacylglycerol lipase ABHD6


(Homo sapiens (Human))		BDBM444465
PNG
(US10662159, Example 54)
Show SMILES COc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1
Show InChI InChI=1S/C17H17F6NO4/c1-26-10-3-2-4-11(5-10)27-12-6-15(7-12)8-24(9-15)14(25)28-13(16(18,19)20)17(21,22)23/h2-5,12-13H,6-9H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MAKSCIENTIFIC, LLC

US Patent


Assay Description
ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...

US Patent US10662159 (2020)


BindingDB Entry DOI: 10.7270/Q2RB77NZ
More data for this
Ligand-Target Pair