null
SMILES: Fc1cccc(OC2C[C@@]3(C2)CCN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1
InChI Key: InChIKey=JEZHOHWWILAWFK-BXLZQBSDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM444476 (US10662159, Example 57) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl... | US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444476 (US10662159, Example 57) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ | |||||||||||
More data for this Ligand-Target Pair |