BDBM44450 (3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluoromethyl)thiazol-2-yl]amine::MLS000085296::N-[(3,5-dimethyl-1-pyrazolyl)methyl]-4-(trifluoromethyl)-2-thiazolamine::N-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-(trifluoromethyl)-1,3-thiazol-2-amine::N-[(3,5-dimethylpyrazol-1-yl)methyl]-4-(trifluoromethyl)-1,3-thiazol-2-amine::SMR000020034::cid_3244409

SMILES: Cc1cc(C)n(CNc2nc(cs2)C(F)(F)F)n1

InChI Key: InChIKey=KCEKBUJLKKSISN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 44450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 4 (Mus musculus)	BDBM44450 ((3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluorometh...) Show SMILES Cc1cc(C)n(CNc2nc(cs2)C(F)(F)F)n1 Show InChI InChI=1S/C10H11F3N4S/c1-6-3-7(2)17(16-6)5-14-9-15-8(4-18-9)10(11,12)13/h3-4H,5H2,1-2H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2P55KW4
					More data for this Ligand-Target Pair
Phosphomannomutase 2 (Homo sapiens (Human))	BDBM44450 ((3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluorometh...) Show SMILES Cc1cc(C)n(CNc2nc(cs2)C(F)(F)F)n1 Show InChI InChI=1S/C10H11F3N4S/c1-6-3-7(2)17(16-6)5-14-9-15-8(4-18-9)10(11,12)13/h3-4H,5H2,1-2H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of human purified PMM2				J Med Chem 54: 3661-8 (2011) Article DOI: 10.1021/jm101401a BindingDB Entry DOI: 10.7270/Q28C9WKP
					More data for this Ligand-Target Pair
Mannose-6-phosphate isomerase (Homo sapiens (Human))	BDBM44450 ((3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluorometh...) Show SMILES Cc1cc(C)n(CNc2nc(cs2)C(F)(F)F)n1 Show InChI InChI=1S/C10H11F3N4S/c1-6-3-7(2)17(16-6)5-14-9-15-8(4-18-9)10(11,12)13/h3-4H,5H2,1-2H3,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of human purified phosphomannose isomerase				J Med Chem 54: 3661-8 (2011) Article DOI: 10.1021/jm101401a BindingDB Entry DOI: 10.7270/Q28C9WKP
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 (Mus musculus)	BDBM44450 ((3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluorometh...) Show SMILES Cc1cc(C)n(CNc2nc(cs2)C(F)(F)F)n1 Show InChI InChI=1S/C10H11F3N4S/c1-6-3-7(2)17(16-6)5-14-9-15-8(4-18-9)10(11,12)13/h3-4H,5H2,1-2H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JD4V5T
					More data for this Ligand-Target Pair