null

SMILES: C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(N)c2)cc1

InChI Key: InChIKey=OHDDNRZGDGYKBR-BFQQSILCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445000 (US10668167, Compound 9) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO6S/c1-32-11-10-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-39,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-8-6-19(7-9-20)18-45-23-5-3-4-21(38)12-23/h3-13,24-25,27-28,30-31,39,41H,14-18,38H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM445000 (US10668167, Compound 9) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO6S/c1-32-11-10-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-39,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-8-6-19(7-9-20)18-45-23-5-3-4-21(38)12-23/h3-13,24-25,27-28,30-31,39,41H,14-18,38H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen® TR-FRET Androgen Receptor Coactivator Assay ...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM445000 (US10668167, Compound 9) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO6S/c1-32-11-10-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-39,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-8-6-19(7-9-20)18-45-23-5-3-4-21(38)12-23/h3-13,24-25,27-28,30-31,39,41H,14-18,38H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM445000 (US10668167, Compound 9) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO6S/c1-32-11-10-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-39,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-8-6-19(7-9-20)18-45-23-5-3-4-21(38)12-23/h3-13,24-25,27-28,30-31,39,41H,14-18,38H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair