null

SMILES: C[C@@H](c1ccc(N)cc1)c1ccc(cc1)[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO

InChI Key: InChIKey=MXEOXTXWJGNBGH-RNCXWHAWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445028 (US10668167, Compound 36) Show SMILES C[C@@H](c1ccc(N)cc1)c1ccc(cc1)[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:30,t:26| Show InChI InChI=1S/C36H39F2NO6/c1-19(21-8-10-23(39)11-9-21)20-4-6-22(7-5-20)32-44-31-16-25-26-15-28(37)27-14-24(41)12-13-33(27,2)35(26,38)29(42)17-34(25,3)36(31,45-32)30(43)18-40/h4-14,19,25-26,28-29,31-32,40,42H,15-18,39H2,1-3H3/t19-,25+,26+,28+,29+,31-,32-,33+,34+,35+,36-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM445028 (US10668167, Compound 36) Show SMILES C[C@@H](c1ccc(N)cc1)c1ccc(cc1)[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:30,t:26| Show InChI InChI=1S/C36H39F2NO6/c1-19(21-8-10-23(39)11-9-21)20-4-6-22(7-5-20)32-44-31-16-25-26-15-28(37)27-14-24(41)12-13-33(27,2)35(26,38)29(42)17-34(25,3)36(31,45-32)30(43)18-40/h4-14,19,25-26,28-29,31-32,40,42H,15-18,39H2,1-3H3/t19-,25+,26+,28+,29+,31-,32-,33+,34+,35+,36-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen® TR-FRET Androgen Receptor Coactivator Assay ...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM445028 (US10668167, Compound 36) Show SMILES C[C@@H](c1ccc(N)cc1)c1ccc(cc1)[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:30,t:26| Show InChI InChI=1S/C36H39F2NO6/c1-19(21-8-10-23(39)11-9-21)20-4-6-22(7-5-20)32-44-31-16-25-26-15-28(37)27-14-24(41)12-13-33(27,2)35(26,38)29(42)17-34(25,3)36(31,45-32)30(43)18-40/h4-14,19,25-26,28-29,31-32,40,42H,15-18,39H2,1-3H3/t19-,25+,26+,28+,29+,31-,32-,33+,34+,35+,36-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM445028 (US10668167, Compound 36) Show SMILES C[C@@H](c1ccc(N)cc1)c1ccc(cc1)[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:30,t:26| Show InChI InChI=1S/C36H39F2NO6/c1-19(21-8-10-23(39)11-9-21)20-4-6-22(7-5-20)32-44-31-16-25-26-15-28(37)27-14-24(41)12-13-33(27,2)35(26,38)29(42)17-34(25,3)36(31,45-32)30(43)18-40/h4-14,19,25-26,28-29,31-32,40,42H,15-18,39H2,1-3H3/t19-,25+,26+,28+,29+,31-,32-,33+,34+,35+,36-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair