null

SMILES: C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(N)cc2)c(O)c1

InChI Key: InChIKey=QZQDZOOHRIJKQN-LZZYNOKFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445041 (US10668167, Compound 51) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(N)cc2)c(O)c1 |r,c:15,t:11| Show InChI InChI=1S/C34H35F2NO8/c1-31-10-9-19(39)12-23(31)24(35)13-22-21-14-29-34(28(42)16-38,32(21,2)15-27(41)33(22,31)36)45-30(44-29)17-3-8-26(25(40)11-17)43-20-6-4-18(37)5-7-20/h3-12,21-22,24,27,29-30,38,40-41H,13-16,37H2,1-2H3/t21-,22-,24-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM445041 (US10668167, Compound 51) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(N)cc2)c(O)c1 |r,c:15,t:11| Show InChI InChI=1S/C34H35F2NO8/c1-31-10-9-19(39)12-23(31)24(35)13-22-21-14-29-34(28(42)16-38,32(21,2)15-27(41)33(22,31)36)45-30(44-29)17-3-8-26(25(40)11-17)43-20-6-4-18(37)5-7-20/h3-12,21-22,24,27,29-30,38,40-41H,13-16,37H2,1-2H3/t21-,22-,24-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen® TR-FRET Androgen Receptor Coactivator Assay ...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM445041 (US10668167, Compound 51) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(N)cc2)c(O)c1 |r,c:15,t:11| Show InChI InChI=1S/C34H35F2NO8/c1-31-10-9-19(39)12-23(31)24(35)13-22-21-14-29-34(28(42)16-38,32(21,2)15-27(41)33(22,31)36)45-30(44-29)17-3-8-26(25(40)11-17)43-20-6-4-18(37)5-7-20/h3-12,21-22,24,27,29-30,38,40-41H,13-16,37H2,1-2H3/t21-,22-,24-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM445041 (US10668167, Compound 51) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(N)cc2)c(O)c1 |r,c:15,t:11| Show InChI InChI=1S/C34H35F2NO8/c1-31-10-9-19(39)12-23(31)24(35)13-22-21-14-29-34(28(42)16-38,32(21,2)15-27(41)33(22,31)36)45-30(44-29)17-3-8-26(25(40)11-17)43-20-6-4-18(37)5-7-20/h3-12,21-22,24,27,29-30,38,40-41H,13-16,37H2,1-2H3/t21-,22-,24-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.6	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair