null

SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Sc2cccc(N)c2)cc1

InChI Key: InChIKey=SIMVLEKLLFIFBJ-ZAHWGWTDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM445048 (US10668167, Compound 60) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Sc2cccc(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C34H37NO6S/c1-32-13-12-22(37)14-20(32)8-11-25-26-16-29-34(28(39)18-36,33(26,2)17-27(38)30(25)32)41-31(40-29)19-6-9-23(10-7-19)42-24-5-3-4-21(35)15-24/h3-7,9-10,12-15,25-27,29-31,36,38H,8,11,16-18,35H2,1-2H3/t25-,26-,27-,29+,30+,31+,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM445048 (US10668167, Compound 60) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Sc2cccc(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C34H37NO6S/c1-32-13-12-22(37)14-20(32)8-11-25-26-16-29-34(28(39)18-36,33(26,2)17-27(38)30(25)32)41-31(40-29)19-6-9-23(10-7-19)42-24-5-3-4-21(35)15-24/h3-7,9-10,12-15,25-27,29-31,36,38H,8,11,16-18,35H2,1-2H3/t25-,26-,27-,29+,30+,31+,32-,33-,34+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM445048 (US10668167, Compound 60) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Sc2cccc(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C34H37NO6S/c1-32-13-12-22(37)14-20(32)8-11-25-26-16-29-34(28(39)18-36,33(26,2)17-27(38)30(25)32)41-31(40-29)19-6-9-23(10-7-19)42-24-5-3-4-21(35)15-24/h3-7,9-10,12-15,25-27,29-31,36,38H,8,11,16-18,35H2,1-2H3/t25-,26-,27-,29+,30+,31+,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	69.9	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...				US Patent US10668167 (2020) BindingDB Entry DOI: 10.7270/Q2B56NSW
					More data for this Ligand-Target Pair