null

SMILES: CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccc(Cl)cc1

InChI Key: InChIKey=NYHSLNVRVJOYFH-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445122 ((S)-N-(4-(4- chlorophenyl)thiazol- 2-yl)-1-cyano-N...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN4OS/c1-20(15(22)14-3-2-8-21(14)10-18)16-19-13(9-23-16)11-4-6-12(17)7-5-11/h4-7,9,14H,2-3,8H2,1H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445122 ((S)-N-(4-(4- chlorophenyl)thiazol- 2-yl)-1-cyano-N...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN4OS/c1-20(15(22)14-3-2-8-21(14)10-18)16-19-13(9-23-16)11-4-6-12(17)7-5-11/h4-7,9,14H,2-3,8H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445122 ((S)-N-(4-(4- chlorophenyl)thiazol- 2-yl)-1-cyano-N...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN4OS/c1-20(15(22)14-3-2-8-21(14)10-18)16-19-13(9-23-16)11-4-6-12(17)7-5-11/h4-7,9,14H,2-3,8H2,1H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445122 ((S)-N-(4-(4- chlorophenyl)thiazol- 2-yl)-1-cyano-N...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN4OS/c1-20(15(22)14-3-2-8-21(14)10-18)16-19-13(9-23-16)11-4-6-12(17)7-5-11/h4-7,9,14H,2-3,8H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair