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SMILES: FC(F)(F)c1n[nH]cc1-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N

InChI Key: InChIKey=UJEGNFZIQZQITK-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES FC(F)(F)c1n[nH]cc1-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N Show InChI InChI=1S/C18H16F3N5O/c19-18(20,21)16-14(7-23-24-16)11-3-4-12-8-26(9-13(12)6-11)17(27)15-2-1-5-25(15)10-22/h3-4,6-7,15H,1-2,5,8-9H2,(H,23,24)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020)
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES FC(F)(F)c1n[nH]cc1-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N Show InChI InChI=1S/C18H16F3N5O/c19-18(20,21)16-14(7-23-24-16)11-3-4-12-8-26(9-13(12)6-11)17(27)15-2-1-5-25(15)10-22/h3-4,6-7,15H,1-2,5,8-9H2,(H,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES FC(F)(F)c1n[nH]cc1-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N Show InChI InChI=1S/C18H16F3N5O/c19-18(20,21)16-14(7-23-24-16)11-3-4-12-8-26(9-13(12)6-11)17(27)15-2-1-5-25(15)10-22/h3-4,6-7,15H,1-2,5,8-9H2,(H,23,24)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES FC(F)(F)c1n[nH]cc1-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N Show InChI InChI=1S/C18H16F3N5O/c19-18(20,21)16-14(7-23-24-16)11-3-4-12-8-26(9-13(12)6-11)17(27)15-2-1-5-25(15)10-22/h3-4,6-7,15H,1-2,5,8-9H2,(H,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020)
					More data for this Ligand-Target Pair