null

SMILES: O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1n[nH]c2ncccc12

InChI Key: InChIKey=ITVHSCOFHWBGHL-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445165 ((S)-2-(4-(1H-pyrazolo[3,4- b]pyridin-3-yl)indoline...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1n[nH]c2ncccc12 Show InChI InChI=1S/C20H18N6O/c21-12-25-10-3-7-17(25)20(27)26-11-8-13-14(4-1-6-16(13)26)18-15-5-2-9-22-19(15)24-23-18/h1-2,4-6,9,17H,3,7-8,10-11H2,(H,22,23,24)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445165 ((S)-2-(4-(1H-pyrazolo[3,4- b]pyridin-3-yl)indoline...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1n[nH]c2ncccc12 Show InChI InChI=1S/C20H18N6O/c21-12-25-10-3-7-17(25)20(27)26-11-8-13-14(4-1-6-16(13)26)18-15-5-2-9-22-19(15)24-23-18/h1-2,4-6,9,17H,3,7-8,10-11H2,(H,22,23,24)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445165 ((S)-2-(4-(1H-pyrazolo[3,4- b]pyridin-3-yl)indoline...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1n[nH]c2ncccc12 Show InChI InChI=1S/C20H18N6O/c21-12-25-10-3-7-17(25)20(27)26-11-8-13-14(4-1-6-16(13)26)18-15-5-2-9-22-19(15)24-23-18/h1-2,4-6,9,17H,3,7-8,10-11H2,(H,22,23,24)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445165 ((S)-2-(4-(1H-pyrazolo[3,4- b]pyridin-3-yl)indoline...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1n[nH]c2ncccc12 Show InChI InChI=1S/C20H18N6O/c21-12-25-10-3-7-17(25)20(27)26-11-8-13-14(4-1-6-16(13)26)18-15-5-2-9-22-19(15)24-23-18/h1-2,4-6,9,17H,3,7-8,10-11H2,(H,22,23,24)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair