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SMILES: COc1ccc(nc1C#N)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N

InChI Key: InChIKey=APFKLZAHDDDAOH-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445173 ((S)-1-Cyano-N-(4-(6-cyano-5-methoxypyridin-2-yl)th...) Show SMILES COc1ccc(nc1C#N)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N |r| Show InChI InChI=1S/C17H16N6O2S/c1-22(16(24)14-4-3-7-23(14)10-19)17-21-13(9-26-17)11-5-6-15(25-2)12(8-18)20-11/h5-6,9,14H,3-4,7H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445173 ((S)-1-Cyano-N-(4-(6-cyano-5-methoxypyridin-2-yl)th...) Show SMILES COc1ccc(nc1C#N)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N |r| Show InChI InChI=1S/C17H16N6O2S/c1-22(16(24)14-4-3-7-23(14)10-19)17-21-13(9-26-17)11-5-6-15(25-2)12(8-18)20-11/h5-6,9,14H,3-4,7H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair