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SMILES: Cc1nnc([nH]1)-c1cc2N(CCc2c(c1)-c1cccc(c1)C#N)C(=O)[C@@H]1CCCN1C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445176 ((S)-2-(4-(3-Cyanophenyl)-6-(5-methyl-4H-1,2,4-tria...) Show SMILES Cc1nnc([nH]1)-c1cc2N(CCc2c(c1)-c1cccc(c1)C#N)C(=O)[C@@H]1CCCN1C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445176 ((S)-2-(4-(3-Cyanophenyl)-6-(5-methyl-4H-1,2,4-tria...) Show SMILES Cc1nnc([nH]1)-c1cc2N(CCc2c(c1)-c1cccc(c1)C#N)C(=O)[C@@H]1CCCN1C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair