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SMILES: COCCOc1ccc(nc1-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N)C#N

InChI Key: InChIKey=BBZPOMQJPPJJMO-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445202 ((S)-1-cyano-N-(4-(6-cyano-3-(2-methoxyethoxy)pyrid...) Show SMILES COCCOc1ccc(nc1-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N)C#N |r| Show InChI InChI=1S/C19H20N6O3S/c1-24(18(26)15-4-3-7-25(15)12-21)19-23-14(11-29-19)17-16(28-9-8-27-2)6-5-13(10-20)22-17/h5-6,11,15H,3-4,7-9H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM445202 ((S)-1-cyano-N-(4-(6-cyano-3-(2-methoxyethoxy)pyrid...) Show SMILES COCCOc1ccc(nc1-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N)C#N |r| Show InChI InChI=1S/C19H20N6O3S/c1-24(18(26)15-4-3-7-25(15)12-21)19-23-14(11-29-19)17-16(28-9-8-27-2)6-5-13(10-20)22-17/h5-6,11,15H,3-4,7-9H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair