null
SMILES: CCn1c2nc(Cc3cn4ccccc4n3)n(Cc3ccc(cc3)-c3ncccn3)c2c(=O)[nH]c1=O
InChI Key: InChIKey=FTJJBFCHNOJGSV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM445671 (Ex. 9/KM-06-89/(I-9) | US10683309, Example 9 | US1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 288 | n/a | n/a | n/a | n/a | n/a | n/a |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent | Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ... | US Patent US10683309 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human)) | BDBM445671 (Ex. 9/KM-06-89/(I-9) | US10683309, Example 9 | US1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent | Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ... | US Patent US11028104 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM445671 (Ex. 9/KM-06-89/(I-9) | US10683309, Example 9 | US1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 288 | n/a | n/a | n/a | n/a | n/a | n/a |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent | Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ... | US Patent US11028104 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human)) | BDBM445671 (Ex. 9/KM-06-89/(I-9) | US10683309, Example 9 | US1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent | Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ... | US Patent US10683309 (2020) | |||||||||||
More data for this Ligand-Target Pair |