BDBM44621 (1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-(4-hydroxybenzyl)spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-indoline]-2',4,6-trione::(1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-[(4-hydroxyphenyl)methyl]spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione::MLS000042296::SMR000048044::cid_5390035

SMILES: Oc1c2[C@H](Cc3ccc(O)cc3)N[C@]3(C(=O)Nc4ccccc34)c2c(O)n1-c1ccc(F)cc1

InChI Key: InChIKey=KAQXJPZYBLUYNZ-FNZWTVRRSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 44621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM44621 ((1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-(4-hydroxyben...) Show SMILES Oc1c2[C@H](Cc3ccc(O)cc3)N[C@]3(C(=O)Nc4ccccc34)c2c(O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C26H20FN3O4/c27-15-7-9-16(10-8-15)30-23(32)21-20(13-14-5-11-17(31)12-6-14)29-26(22(21)24(30)33)18-3-1-2-4-19(18)28-25(26)34/h1-12,20,29,31-33H,13H2,(H,28,34)/t20-,26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.88E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q25719FH
					More data for this Ligand-Target Pair