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SMILES: COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1cncc(C)c1

InChI Key: InChIKey=QLBSWEJGFDUDSZ-OXJNMPFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447694   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447694
PNG
(US10689367, Example 13.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C23H32ClN7O5S/c1-14(2)36-20(21-26-10-18(24)11-27-21)16(4)37(32,33)30-23-29-28-22(17-7-15(3)8-25-9-17)31(23)19(12-34-5)13-35-6/h7-11,14,16,19-20H,12-13H2,1-6H3,(H,29,30)/t16-,20+/m0/s1
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US Patent
n/an/an/an/a 80n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair