BindingDB logo
myBDB logout

null

SMILES: COCCOc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)n1C(COC)COC

InChI Key: InChIKey=OKZLYZLUBDLDKZ-YWZLYKJASA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447711   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447711
PNG
(US10689367, Example 42.0)
Show SMILES COCCOc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)n1C(COC)COC |r|
Show InChI InChI=1S/C23H32ClN7O7S/c1-15(20(37-5)21-25-11-16(24)12-26-21)39(32,33)30-23-29-28-22(31(23)17(13-35-3)14-36-4)18-7-6-8-19(27-18)38-10-9-34-2/h6-8,11-12,15,17,20H,9-10,13-14H2,1-5H3,(H,29,30)/t15-,20-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 17n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair