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SMILES: COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1

InChI Key: InChIKey=SBXXCQXGOJVJAB-BBRMVZONSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447742   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447742
PNG
(US10689367, Example 61.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C20H24ClN7O4S/c1-13(16(32-3)17-23-10-14(21)11-24-17)33(29,30)27-19-26-25-18(15-6-4-5-9-22-15)28(19)20(7-8-20)12-31-2/h4-6,9-11,13,16H,7-8,12H2,1-3H3,(H,26,27)/t13-,16-/m0/s1
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PC cid
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US Patent
n/an/an/an/a 0.890n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair