null
SMILES: Cc1ccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)o1
InChI Key: InChIKey=PVNFHDUJWZPDNI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SRSF protein kinase 1 (Homo sapiens (Human)) | BDBM448657 (N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 21.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonate Limited US Patent | Assay Description Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ... | US Patent US10696661 (2020) | |||||||||||
More data for this Ligand-Target Pair |