null
SMILES: FC(F)(F)c1ccc(N2CCN(Cc3cscn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1
InChI Key: InChIKey=GXESAQKBZJNLLD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SRSF protein kinase 1 (Homo sapiens (Human)) | BDBM448667 (5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piper...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 13.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonate Limited US Patent | Assay Description Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ... | US Patent US10696661 (2020) | |||||||||||
More data for this Ligand-Target Pair |