null
SMILES: FC(F)(F)c1ccc(N2CCN(Cc3cncs3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1
InChI Key: InChIKey=HINAXCLUTGMTNH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SRSF protein kinase 1 (Homo sapiens (Human)) | BDBM448668 (5-(pyridin-4-yl)-N-(2-(5-(thiazol-2-ylmethyl)piper...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 27.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonate Limited US Patent | Assay Description Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ... | US Patent US10696661 (2020) BindingDB Entry DOI: 10.7270/Q23B635R | |||||||||||
More data for this Ligand-Target Pair |