BDBM4493 4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxyquinazoline::6,7-Dimethoxyquinazoline deriv. 3::N-(2,4-dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine::quinazoline deriv. 3a

SMILES: COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OC

InChI Key: InChIKey=PKEYRKYHSXFGBA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4493 (4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxyquinazo...) Show SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OC Show InChI InChI=1S/C16H13Cl2N3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4493 (4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxyquinazo...) Show SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OC Show InChI InChI=1S/C16H13Cl2N3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 822-33 (2001) Article DOI: 10.1021/jm000420z BindingDB Entry DOI: 10.7270/Q2Z31WVP
					More data for this Ligand-Target Pair