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SMILES: Cc1ncnc2n(ccc12)[C@@H]1C[C@H]([C@H](O)c2ccc(F)c(F)c2)[C@@H](O)[C@H]1O

InChI Key: InChIKey=PJRBJFLQEDJNPM-YXWSMURKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451167   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM451167
PNG
(US10709709, Example 3)
Show SMILES Cc1ncnc2n(ccc12)[C@@H]1C[C@H]([C@H](O)c2ccc(F)c(F)c2)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H19F2N3O3/c1-9-11-4-5-24(19(11)23-8-22-9)15-7-12(17(26)18(15)27)16(25)10-2-3-13(20)14(21)6-10/h2-6,8,12,15-18,25-27H,7H2,1H3/t12-,15-,16-,17-,18+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...

US Patent US10709709 (2020)


BindingDB Entry DOI: 10.7270/Q26113CC
More data for this
Ligand-Target Pair