null
SMILES: Cc1cc2CCNCc2c(O[C@H]2C[C@H]([C@H](O)[C@@H]2O)n2cc(Cl)c3c(N)ncnc23)c1
InChI Key: InChIKey=LFMSIFZDQXVWRB-TWKWOARYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein arginine N-methyltransferase 5 (Homo sapiens (Human)) | BDBM451302 (US10709709, Example 129) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a... | US Patent US10709709 (2020) | |||||||||||
More data for this Ligand-Target Pair |