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SMILES: Nc1ncc(cc1-c1ccc2c(c1)nc[nH]c2=O)-c1cccc2ncsc12

InChI Key: InChIKey=UVSMTBSUZIWXNK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 4 (Homo sapiens (Human))	BDBM451754 (7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...) Show SMILES Nc1ncc(cc1-c1ccc2c(c1)nc[nH]c2=O)-c1cccc2ncsc12 Show InChI InChI=1S/C20H13N5OS/c21-19-15(11-4-5-14-17(7-11)23-9-24-20(14)26)6-12(8-22-19)13-2-1-3-16-18(13)27-10-25-16/h1-10H,(H2,21,22)(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451754 (7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...) Show SMILES Nc1ncc(cc1-c1ccc2c(c1)nc[nH]c2=O)-c1cccc2ncsc12 Show InChI InChI=1S/C20H13N5OS/c21-19-15(11-4-5-14-17(7-11)23-9-24-20(14)26)6-12(8-22-19)13-2-1-3-16-18(13)27-10-25-16/h1-10H,(H2,21,22)(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451754 (7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...) Show SMILES Nc1ncc(cc1-c1ccc2c(c1)nc[nH]c2=O)-c1cccc2ncsc12 Show InChI InChI=1S/C20H13N5OS/c21-19-15(11-4-5-14-17(7-11)23-9-24-20(14)26)6-12(8-22-19)13-2-1-3-16-18(13)27-10-25-16/h1-10H,(H2,21,22)(H,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair