null

SMILES: Cc1cnn2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc4cnn(C)c4c3)c(=O)c12

InChI Key: InChIKey=OGLFBGKKIABWEQ-DOTOQJQBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452660 (5-methyl-3-((3- ((3R,5R)-5-(1-methyl- 1H-indazol-6...) Show SMILES Cc1cnn2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc4cnn(C)c4c3)c(=O)c12 |r| Show InChI InChI=1S/C21H20N8O3/c1-12-7-23-29-19(12)21(30)28(11-24-29)9-18-25-20(26-32-18)15-6-17(31-10-15)13-3-4-14-8-22-27(2)16(14)5-13/h3-5,7-8,11,15,17H,6,9-10H2,1-2H3/t15-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452660 (5-methyl-3-((3- ((3R,5R)-5-(1-methyl- 1H-indazol-6...) Show SMILES Cc1cnn2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc4cnn(C)c4c3)c(=O)c12 |r| Show InChI InChI=1S/C21H20N8O3/c1-12-7-23-29-19(12)21(30)28(11-24-29)9-18-25-20(26-32-18)15-6-17(31-10-15)13-3-4-14-8-22-27(2)16(14)5-13/h3-5,7-8,11,15,17H,6,9-10H2,1-2H3/t15-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.26	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair