null

SMILES: Cn1c2c(ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c2=O)oc1=O

InChI Key: InChIKey=GFRTYOMOOHPBGT-WCQYABFASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452675 (1-methyl-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)te...) Show SMILES Cn1c2c(ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c2=O)oc1=O |r| Show InChI InChI=1S/C19H16ClN5O5/c1-24-15-17(29-19(24)27)21-9-25(18(15)26)7-14-22-16(23-30-14)11-6-13(28-8-11)10-2-4-12(20)5-3-10/h2-5,9,11,13H,6-8H2,1H3/t11-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452675 (1-methyl-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)te...) Show SMILES Cn1c2c(ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c2=O)oc1=O |r| Show InChI InChI=1S/C19H16ClN5O5/c1-24-15-17(29-19(24)27)21-9-25(18(15)26)7-14-22-16(23-30-14)11-6-13(28-8-11)10-2-4-12(20)5-3-10/h2-5,9,11,13H,6-8H2,1H3/t11-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.35	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair