null

SMILES: Nc1nc2ncsc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1

InChI Key: InChIKey=BGJCZTPFRKSUHS-CMPLNLGQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452680 (5-amino-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)tet...) Show SMILES Nc1nc2ncsc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H15ClN6O3S/c19-11-3-1-9(2-4-11)12-5-10(7-27-12)15-22-13(28-24-15)6-25-17(26)14-16(21-8-29-14)23-18(25)20/h1-4,8,10,12H,5-7H2,(H2,20,23)/t10-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM452680 (5-amino-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)tet...) Show SMILES Nc1nc2ncsc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H15ClN6O3S/c19-11-3-1-9(2-4-11)12-5-10(7-27-12)15-22-13(28-24-15)6-25-17(26)14-16(21-8-29-14)23-18(25)20/h1-4,8,10,12H,5-7H2,(H2,20,23)/t10-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.73	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...				US Patent US10710994 (2020)
					More data for this Ligand-Target Pair