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SMILES: CCn1c2ccc(cc2c2cc(C)cc(F)c12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O

InChI Key: InChIKey=SFNDGBGUJRCQSC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453702   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))		BDBM453702
PNG
(2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-1-(...)
Show SMILES CCn1c2ccc(cc2c2cc(C)cc(F)c12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O
Show InChI InChI=1S/C27H26FN3O3/c1-5-30-22-8-6-17(14-19(22)20-12-15(2)13-21(28)25(20)30)26-29-24-16(3)18(27(32)33)7-9-23(24)31(26)10-11-34-4/h6-9,12-14H,5,10-11H2,1-4H3,(H,32,33)
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US Patent
n/an/a 2.40n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...

US Patent US10730856 (2020)

More data for this
Ligand-Target Pair