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SMILES: CC1(C)CCn2ncc(c2C1)-c1cc(NC(=O)[C@H]2CCC[C@@H](N)C2)ncc1F

InChI Key: InChIKey=CHRZVGRJOMIBAW-UONOGXRCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM454571 (US10717746, Example 51a) Show SMILES CC1(C)CCn2ncc(c2C1)-c1cc(NC(=O)[C@H]2CCC[C@@H](N)C2)ncc1F |r| Show InChI InChI=1S/C21H28FN5O/c1-21(2)6-7-27-18(10-21)16(11-25-27)15-9-19(24-12-17(15)22)26-20(28)13-4-3-5-14(23)8-13/h9,11-14H,3-8,10,23H2,1-2H3,(H,24,26,28)/t13-,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent					Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...				US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM454571 (US10717746, Example 51a) Show SMILES CC1(C)CCn2ncc(c2C1)-c1cc(NC(=O)[C@H]2CCC[C@@H](N)C2)ncc1F |r| Show InChI InChI=1S/C21H28FN5O/c1-21(2)6-7-27-18(10-21)16(11-25-27)15-9-19(24-12-17(15)22)26-20(28)13-4-3-5-14(23)8-13/h9,11-14H,3-8,10,23H2,1-2H3,(H,24,26,28)/t13-,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent					Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...				US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F
					More data for this Ligand-Target Pair