Found 5 hits for monomerid = 454582 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454582
(US10717746, Example 63)Show SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(F)cn1 |r| Show InChI InChI=1S/C21H26FN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description
Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454582
(US10717746, Example 63)Show SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(F)cn1 |r| Show InChI InChI=1S/C21H26FN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description
Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454582
(US10717746, Example 63)Show SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(F)cn1 |r| Show InChI InChI=1S/C21H26FN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01754
BindingDB Entry DOI: 10.7270/Q2M90D8V |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454582
(US10717746, Example 63)Show SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(F)cn1 |r| Show InChI InChI=1S/C21H26FN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01754
BindingDB Entry DOI: 10.7270/Q2M90D8V |
More data for this
Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454582
(US10717746, Example 63)Show SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(F)cn1 |r| Show InChI InChI=1S/C21H26FN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01754
BindingDB Entry DOI: 10.7270/Q2M90D8V |
More data for this
Ligand-Target Pair | |
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