null

SMILES: CC(C)[C@H](N1Cc2cccc(C#N)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C

InChI Key: InChIKey=FLXRXNAKENRCSS-USZFVNFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM454884 (US10730870, Example 47) Show SMILES CC(C)[C@H](N1Cc2cccc(C#N)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-6-4-5-21(12-31)25(22)29(35)38)30(39)34-15-23(36)11-24(34)28(37)32-13-19-7-9-20(10-8-19)27-18(3)33-16-40-27/h4-10,16-17,23-24,26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,24+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
ARVINAS OPERATIONS, INC.; YALE UNIVERSITY US Patent					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				US Patent US10730870 (2020)
					More data for this Ligand-Target Pair
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM454884 (US10730870, Example 47) Show SMILES CC(C)[C@H](N1Cc2cccc(C#N)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-6-4-5-21(12-31)25(22)29(35)38)30(39)34-15-23(36)11-24(34)28(37)32-13-19-7-9-20(10-8-19)27-18(3)33-16-40-27/h4-10,16-17,23-24,26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,24+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
ARVINAS OPERATIONS, INC.; YALE UNIVERSITY US Patent					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				US Patent US10730870 (2020)
					More data for this Ligand-Target Pair