null

SMILES: COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)Cc2ccc(C)nn2)nnc1-c1ccc(C)o1

InChI Key: InChIKey=SYZRTXZDUYXWMK-INIZCTEOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM456594 (US10736883, Example 31.0) Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)Cc2ccc(C)nn2)nnc1-c1ccc(C)o1 |r,wU:16.17,(-5.44,-5.53,;-3.95,-5.93,;-2.86,-4.84,;-3.26,-3.35,;-2.17,-2.27,;-.69,-2.66,;-.29,-4.15,;1.2,-4.55,;2.29,-3.46,;-1.38,-5.24,;-.87,-7.23,;.46,-8,;1.8,-7.23,;3.13,-8,;2.36,-9.34,;4.46,-8.77,;3.9,-6.67,;3.13,-5.34,;5.44,-6.67,;6.21,-5.34,;7.75,-5.34,;8.52,-4,;7.75,-2.67,;8.52,-1.34,;6.21,-2.67,;5.44,-4,;.14,-9.51,;-1.39,-9.67,;-2.01,-8.26,;-3.5,-7.87,;-4.2,-6.49,;-5.72,-6.73,;-5.96,-8.26,;-7.3,-9.03,;-4.59,-8.95,)| Show InChI InChI=1S/C23H26N6O5S/c1-14-9-11-17(25-24-14)13-16(3)35(30,31)28-23-27-26-22(20-12-10-15(2)34-20)29(23)21-18(32-4)7-6-8-19(21)33-5/h6-12,16H,13H2,1-5H3,(H,27,28)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...				US Patent US10736883 (2020)
					More data for this Ligand-Target Pair